Pathobiology of Human Disease

Pathobiology of Human Disease

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Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of qNormalq and qDiseaseq anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutionsNote how the selection of contours might affect how one interprets that data; (i) a 2D zebra plot that combines densities with contours; ... Plots were made using FlowJo (TreeStar software). this phenomenon in order to more readily visualize and interpret the data. ... cytometry in which eight to eighteen fluorescent probes are detected simultaneously makes manual compensation a practical impossibility.

Title:Pathobiology of Human Disease
Publisher:Elsevier - 2014-08-01

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